Gene description for MMP2
Gene name matrix metallopeptidase 2
Gene symbol MMP2
Other names/aliases CLG4
CLG4A
MMP-2
MMP-II
MONA
TBE-1
Species Homo sapiens
 Experiment description of studies that identified MMP2 in Ovarian cancer cells

1
Experiment ID316
Identified moleculeprotein
Extracellular vesicle typeMicrovesicles
MISEVEVs
Identification method Zymography
PubMed ID 18472965   
OrganismHomo sapiens
Experiment descriptionCathepsin B mediates the pH-dependent proinvasive activity of tumor-shed microvesicles
AuthorsGiusti I, D'Ascenzo S, Millimaggi D, Taraboletti G, Carta G, Franceschini N, Pavan A, Dolo V
Journal name Neoplasia
Publication year2008
SampleOvarian cancer cells
Sample nameCABA I
Isolation/purification methodsDifferential centrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyWesten blotting
Zymography
EV-TRACK -

2
Experiment ID629
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleOvarian cancer cells
Sample nameOVCAR-5
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -

3
Experiment ID631
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleOvarian cancer cells
Sample nameSK-OV-3
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -

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